In Vitro Expression of the CtsK Gene in Bacterial Expression System, Escherichia coli Cathepsin K encoded by the CtsK gene is an enzyme responsible for bone remodeling through ossification in human. Therefore, it could be used as an effective treatment approach for a variety of orthopedic disorders including bone fractures. With the availability of recombinant…
Development of Inflammatory Biomarker Panel for Laboratory-Based Depression Diagnosis: A Sri Lankan Twin Study. (IMiD Project) Currently depression is diagnosed through questionnaire base protocols by a healthcare professional. However, due to overlapping clinical characteristics of different psychoneurological disorders often misdiagnoses are common, there is a rising demand for a biological test for depression specific diagnosis.…
CoTaSS 2 Follow-up study – IRD Bio-bank The Colombo Twin and Singleton Follow-up Study (CoTaSS2), which is a ‘population based twin study of psychiatric disorders and metabolic syndrome in Sri Lanka’ was one of main projects completed during the year 2015-16. DNA extractions were carried out from 3483 samples of whole blood samples of twin…
Expression of Estrogen Receptor α in gonads of in-ovo estrogen exposed male chickens (Gallus domesticus) with and without post hatching estrogen treatment. Poultry industry is one of the fast growing livestock industries in the world. One of the key features of the layer industry is, it doesn’t require commercial male chicks for the table egg…
Marker-assisted sex determination of Myristica fragrans cultivars using Random Amplified Polymorphic DNA Markers Nutmeg plants (Myristica fragrans) can be characterized as dioecious (where male and female flowers are located on different trees). Out of two types of trees only female plants bear the economically valued nutmeg fruits. In a plantation, the ratio of male to…
A study on Date palm ( Phoenix dactylifera ) and Ceylon date palm ( Phoenix pusilla ) germplasm in Sri Lanka Date palm is a popular fruit among Sri Lankans with less number of significance scientific studies. In Sri Lanka, both Date palm and Ceylon date palm are naturally raised in Northern and Eastern provinces.…
Phenotypic characterisation and molecular phylogenetics of the endemic skink genus, Lankascincus (Squamata: Scincidae) in Sri Lanka and its conservation aspects Lineage of Lankascincus genus and the skink family classification have been controversial in recent past. The morphological analysis of these species has failed to recognize these species’ position in the genus. Therefore molecular level analysis…